Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | HLCS | P50747 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28157478 | 0.87 | TDP1 (0.76) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL28298433 | 0.86 | HLCS (0.76) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL479444 | 0.85 | HLCS (0.72) | TDP1HLCSMEN1ABL1LMNA | |
| Hydrochloric Acid SCHEMBL7374429 | 0.84 | HLCS (0.70) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL28283183 | 0.83 | TDP1 (0.81) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL21176811 | 0.83 | TDP1 (0.81) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL28119479 | 0.83 | TDP1 (0.81) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL21114407 | 0.83 | TDP1 (0.81) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL22265330 | 0.82 | TDP1 (0.79) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL28516340 | 0.81 | TDP1 (0.73) | TDP1HLCSMEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656742-A | Ring-opened purine compounds for labeling polynucleotides | UNIVERSITY OF MIAMI (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0625985-B1 | METHOD AND RING-OPENED PURINE COMPOUNDS FOR LABELING POLYNUCLEOTIDES | UNIV MIAMI (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5593829-A | Method for labeling DNA by ring-opening of purine bases | UNIVERSITY OF MIAMI (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0625985-A1 | METHOD AND RING-OPENED PURINE COMPOUNDS FOR LABELING POLYNUCLEOTIDES. | UNIV MIAMI (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993011146-A1 | METHOD AND RING-OPENED PURINE COMPOUNDS FOR LABELING POLYNUCLEOTIDES | UNIVERSITY OF MIAMI (US) | 1993-06-10 | — | — | WO | disclosed |