SCHEMBL479444

SCHEMBL479444

CCCCCC(N)(N)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HLCS P50747 6/20 0.72
TDP1 Q9NUW8 6/20 0.64
MEN1 O00255 1/20 0.64
ABL1 P00519 1/20 0.64
LMNA P02545 1/20 0.64
PKM P14618 1/20 0.64
IDE P14735 1/20 0.64
MAPK1 P28482 1/20 0.64
KMT2A Q03164 1/20 0.64
RIN1 Q13671 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
CA12 O43570 7/20 0.50
CA1 P00915 7/20 0.50
CA2 P00918 7/20 0.50
CA9 Q16790 7/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7374429 0.99 HLCS (0.70) HLCSTDP1MEN1ABL1LMNA
Biotin SCHEMBL8651197 0.85 TDP1 (0.87) HLCSTDP1MEN1ABL1LMNA
Biotin SCHEMBL6033491 0.85 TDP1 (0.87) HLCSTDP1MEN1ABL1LMNA
SCHEMBL17830117 0.85 HLCS (0.82) HLCSTDP1MEN1ABL1LMNA
SCHEMBL479231 0.85 HLCS (0.82) HLCSTDP1MEN1ABL1LMNA
SCHEMBL31028942 0.85 HLCS (0.64) HLCSTDP1MEN1ABL1LMNA
SCHEMBL29467342 0.85 HLCS (0.64) HLCSTDP1MEN1ABL1LMNA
SCHEMBL8760691 0.85 TDP1 (0.64) HLCSTDP1MEN1ABL1LMNA
SCHEMBL10038443 0.85 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA
SCHEMBL11248303 0.85 HLCS (1.00) HLCSTDP1MEN1ABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2411809-B1 LUMINESCENCE ASSAY METHOD OY ARCTIC PARTNERS AB (FI) 2017-05-10 EP disclosed
US-8993246-B2 Luminescence assay method OY ARCTIC PARTNERS AB (FI) 2015-03-31 US disclosed
EP-2411809-A1 LUMINESCENCE ASSAY METHOD OY Arctic Partners AB (FI) 2012-02-01 EP disclosed
US-20120009566-A1 LUMINESCENCE ASSAY METHOD OY ARCTIC PARTNERS AB C/O TIMO LOVGREN (FI) 2012-01-12 US disclosed
WO-2010109065-A1 LUMINESCENCE ASSAY METHOD OY ARCTIC PARTNERS AB (FI) 2010-09-30 WO disclosed