SCHEMBL8760692

SCHEMBL8760692

CC=CC(=O)NC(OC)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.35
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
GFPT1 Q06210 1/20 0.33
HCAR2 Q8TDS4 2/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
ACACB O00763 1/20 0.32
TSHR P16473 1/20 0.31
TP53 P04637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30
SLC1A1 P43005 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL363847 0.81 TSHR (0.52) ALDH1A1GAAGFPT1ACACBTSHR
Methoxymethane SCHEMBL2438449 0.78 ALDH1A1 (0.36) ALDH1A1GAASMN1; SMN2TAS1R3TAS1R1
SCHEMBL9304164 0.74 SMN1; SMN2 (0.47) ALDH1A1GAASMN1; SMN2ACACBTSHR
SCHEMBL9304167 0.74 SMN1; SMN2 (0.47) ALDH1A1GAASMN1; SMN2ACACBTSHR
SCHEMBL9304160 0.74 SMN1; SMN2 (0.47) ALDH1A1GAASMN1; SMN2ACACBTSHR
SCHEMBL1563397 0.74 ALDH1A1 (0.40) ALDH1A1GAASMN1; SMN2ACACBTSHR
SCHEMBL10381604 0.73 KDM4E (0.41) ALDH1A1SMN1; SMN2SLC1A3SLC1A2SLC1A1
SCHEMBL238196 0.71 SLC1A3 (0.38) ALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL28176602 0.71 CA14 (0.42) ALDH1A1GAASMN1; SMN2TAS1R3TAS1R1
SCHEMBL194056 0.71 SMN1; SMN2 (0.33) ALDH1A1GAASMN1; SMN2TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450875-B1 Process for the production of ester derivatives useful as fuels and lubricating oil additives and novel esters produced thereby BP CHEMICALS ADDITIVES (GB) 1997-06-18 EP claimed