Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28220528 | 0.76 | IDO1 (0.50) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL19809204 | 0.75 | HSPA5 (0.48) | IDO1TAAR1NPC1RAB9AKDM4E | |
| SCHEMBL5486703 | 0.73 | IDO1 (0.52) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL6655794 | 0.72 | TAAR1 (0.48) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL1963873 | 0.72 | IDO1 (0.42) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL28335429 | 0.72 | IDO1 (0.52) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL30377 | 0.71 | IDO1 (0.61) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| Phosphine SCHEMBL20719631 | 0.70 | IDO1 (0.59) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL9167140 | 0.69 | SLC6A2 (0.43) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL2804442 | 0.69 | TP53 (0.42) | IDO1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542243-B1 | Thermal disproportionation of organooxysilanes | DOW CORNING (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0542243-A1 | Thermal disproportionation of organooxysilanes | DOW CORNING CORPORATION (US) | 1993-05-19 | — | — | EP | disclosed |
| US-5126472-A | Phenyldialkoxysilanes to diphenyldialkoxysilanes and cycloalkyldialkoxysilanes to dicyclodialkoxysilanes | DOW CORNING CORPORATION (US) | 1992-06-30 | — | — | US | disclosed |