Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486729 | 0.78 | ALDH1A1 (0.43) | IDO1PNMTTAAR1LMNASLC6A2 | |
| SCHEMBL5487166 | 0.76 | TAAR1 (0.56) | IDO1PNMTTAAR1KMT2APKM | |
| SCHEMBL7942042 | 0.75 | ALDH1A1 (0.39) | IDO1PNMTKMT2ATSHR | |
| SCHEMBL7609506 | 0.73 | TAAR1 (0.46) | IDO1TAAR1KMT2ATSHRLMNA | |
| SCHEMBL5081674 | 0.73 | TAAR1 (0.46) | IDO1PNMTTAAR1CYP1A2CYP2D6 | |
| SCHEMBL1066724 | 0.73 | TAAR1 (0.46) | TAAR1KMT2ATSHRLMNANPC1 | |
| SCHEMBL8760758 | 0.73 | IDO1 (0.45) | IDO1PNMTTAAR1KMT2APKM | |
| SCHEMBL672407 | 0.73 | IDO1 (0.62) | IDO1PNMTTAAR1PKMTSHR | |
| SCHEMBL6740216 | 0.73 | TAAR1 (0.71) | IDO1PNMTTAAR1KMT2APKM | |
| SCHEMBL29519238 | 0.73 | IDO1 (0.62) | IDO1PNMTTAAR1PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |