Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516952 | 1.00 | LTA4H (0.53) | LTA4HS1PR1S1PR3NPC1RAB9A | |
| SCHEMBL3954076 | 0.86 | LTA4H (0.67) | LTA4HS1PR1S1PR3SMN1; SMN2TAAR1 | |
| SCHEMBL2309395 | 0.86 | LTA4H (0.67) | LTA4HS1PR1S1PR3SMN1; SMN2TAAR1 | |
| SCHEMBL12886499 | 0.86 | SMN1; SMN2 (0.53) | LTA4HS1PR1S1PR3NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27450918 | 0.84 | LTA4H (0.65) | LTA4HS1PR1S1PR3TAAR1MEN1 | |
| Hydrochloric Acid SCHEMBL7363569 | 0.84 | LTA4H (0.65) | LTA4HS1PR1S1PR3TAAR1MEN1 | |
| Bromide SCHEMBL11428373 | 0.81 | TAAR1 (0.61) | LTA4HNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL8761898 | 0.81 | MMP9 (0.57) | LTA4HMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8761863 | 0.81 | MMP9 (0.57) | LTA4HMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9116086 | 0.81 | LTA4H (0.45) | LTA4HSMN1; SMN2MEN1KMT2AMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779296-A2 | D-alpha-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as intermediates for artificial sweeteners | THE COCA-COLA COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0736037-A1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF L-ASPARTYL-D-$g(a)-AMINOALKANOYL-(S)-N-$g(a)-ALKYLBENZYL AMIDES USEFUL AS ARTIFICIAL SWEETENERS | THE COCA-COLA COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017418-A2 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF L-ASPARTYL-D-α-AMINOALKANOYL-(S)-N-α-ALKYLBENZYL AMIDES USEFUL AS ARTIFICIAL SWEETENERS | THE COCA-COLA COMPANY (US) | 1995-06-29 | — | — | WO | disclosed |
| US-5286509-A | L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners | THE COCA-COLA COMPANY (US) | 1994-02-15 | — | — | US | disclosed |