Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 17/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478588 | 0.83 | LSS (0.66) | LSSKDM4EMEN1MAPTKMT2A | |
| SCHEMBL8760654 | 0.81 | LSS (0.56) | LSS | |
| SCHEMBL8760774 | 0.80 | LSS (0.43) | LSSKDM4E | |
| SCHEMBL8762815 | 0.80 | LSS (0.58) | LSSKDM4E | |
| SCHEMBL8478710 | 0.80 | LSS (0.46) | LSS | |
| SCHEMBL8484710 | 0.78 | LSS (0.55) | LSSKDM4EMEN1MAPTKMT2A | |
| SCHEMBL8760860 | 0.78 | LSS (0.68) | LSS | |
| SCHEMBL8481533 | 0.77 | LSS (0.64) | LSSKDM4EMEN1MAPTKMT2A | |
| SCHEMBL8481531 | 0.76 | LSS (0.50) | LSSMAPT | |
| Fumaric Acid SCHEMBL8761342 | 0.74 | LSS (0.42) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778271-A2 | Aminoalkyl-substituted benzo-heterocyclic compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |