Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.66 |
| ▸ | ESR1 | P03372 | 6/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.66 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SI | P14410 | 3/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335011 | 0.91 | LTA4H (0.50) | LTA4HESR1ESR2PLK1MEN1 | |
| SCHEMBL8761178 | 0.86 | ESR1 (0.70) | LTA4HESR1ESR2NR5A1ABCG2 | |
| 1-Hydroxy-4-Propoxybenzene SCHEMBL56796 | 0.85 | LTA4H (0.88) | LTA4HESR1ESR2NR5A1ABCG2 | |
| SCHEMBL10328457 | 0.84 | LTA4H (0.68) | LTA4HESR1ESR2NR5A1ABCG2 | |
| SCHEMBL10704665 | 0.83 | LTA4H (0.84) | LTA4HESR1ESR2NR5A1ABCG2 | |
| 1-Hydroxy-4-Propoxybenzene SCHEMBL27539049 | 0.83 | LTA4H (0.84) | LTA4HESR1ESR2NR5A1ABCG2 | |
| SCHEMBL258649 | 0.81 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL7908974 | 0.80 | CYP3A4 (0.59) | LTA4HESR1ESR2NR5A1MEN1 | |
| SCHEMBL8760915 | 0.80 | ESR1 (0.73) | LTA4HESR1ESR2GAA | |
| SCHEMBL18857215 | 0.80 | LTA4H (0.62) | LTA4HESR1ESR2NR5A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497465-B1 | Record material | APPLETON PAPER INC (US) | 1997-06-04 | — | — | EP | disclosed |
| EP-0497465-A1 | Record material | APPLETON PAPERS INC. (US) | 1992-08-05 | — | — | EP | disclosed |