Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.73 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25955803 | 0.90 | ESR1 (0.54) | ESR1ESR2GAAAR | |
| SCHEMBL258649 | 0.85 | ESR1 (1.00) | ESR1ESR2AR | |
| SCHEMBL3173618 | 0.85 | ESR2 (0.55) | ESR1ESR2LTA4HCALM1APP | |
| SCHEMBL8761178 | 0.83 | ESR1 (0.70) | ESR1ESR2LTA4HAR | |
| SCHEMBL8760898 | 0.83 | ESR2 (0.53) | ESR1ESR2LTA4HCALM1APP | |
| SCHEMBL1053039 | 0.82 | ESR1 (0.73) | ESR1ESR2AR | |
| SCHEMBL13070216 | 0.81 | LMNA (0.50) | ESR1ESR2LTA4HCALM1APP | |
| SCHEMBL8760893 | 0.80 | LTA4H (0.66) | ESR1ESR2LTA4HGAA | |
| SCHEMBL8761082 | 0.80 | ESR1 (0.66) | ESR1ESR2AR | |
| SCHEMBL6894379 | 0.79 | ESR1 (0.78) | ESR1ESR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497465-B1 | Record material | APPLETON PAPER INC (US) | 1997-06-04 | — | — | EP | disclosed |
| EP-0497465-A1 | Record material | APPLETON PAPERS INC. (US) | 1992-08-05 | — | — | EP | disclosed |