Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353901 | 0.89 | ALDH1A1 (0.32) | ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL9353710 | 0.88 | TSHR (0.31) | TSHRMAPK1NPSR1 | |
| SCHEMBL9353916 | 0.82 | TSHR (0.30) | TSHRMAPK1NPSR1 | |
| SCHEMBL8760912 | 0.81 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL9357369 | 0.80 | KMT2A (0.32) | ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL599846 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1NPSR1BRD4 | |
| SCHEMBL9597854 | 0.74 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPK1NPSR1BRD4 | |
| SCHEMBL7067189 | 0.73 | — | — | |
| SCHEMBL8760090 | 0.72 | UPP1 (0.49) | ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL9353929 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |