Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2027300 | 0.90 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL11631912 | 0.82 | LMNA (0.58) | KMT2AL3MBTL1MEN1CA12CA1 | |
| SCHEMBL30441853 | 0.82 | TDP1 (0.53) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL9629603 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL25576433 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| Hydrochloric Acid SCHEMBL25212066 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL27484782 | 0.76 | SMN1; SMN2 (0.47) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL10855143 | 0.76 | SMN1; SMN2 (0.47) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL10855149 | 0.76 | SMN1; SMN2 (0.47) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL27552966 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767832-A1 | CHIRAL SYNTHESIS OF 2-HYDROXY CARBOXYLIC ACIDS WITH A DEHYDROGENASE | Genzyme Limited (GB) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996001892-A1 | CHIRAL SYNTHESIS OF 2-HYDROXY CARBOXYLIC ACIDS WITH A DEHYDROGENASE | GENZYME LIMITED (GB) | 1996-01-25 | — | — | WO | disclosed |