Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760223 | 0.89 | HTT (0.33) | UPP1HTT | |
| SCHEMBL8760134 | 0.88 | UPP1 (0.38) | UPP1 | |
| SCHEMBL8760090 | 0.85 | UPP1 (0.49) | UPP1 | |
| SCHEMBL8760050 | 0.83 | UPP1 (0.35) | UPP1MEN1KMT2ATDP1HTT | |
| SCHEMBL7758840 | 0.83 | ALDH1A1 (0.51) | UPP1MEN1KMT2AHTT | |
| SCHEMBL6087421 | 0.79 | SMN1; SMN2 (0.37) | MEN1KMT2ATDP1HTT | |
| SCHEMBL7758302 | 0.79 | SMN1; SMN2 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL7758304 | 0.79 | SMN1; SMN2 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL8392462 | 0.79 | UPP1 (0.39) | UPP1MEN1KMT2ATDP1HTT | |
| SCHEMBL5199239 | 0.79 | UPP1 (0.44) | UPP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | claimed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | claimed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | claimed |
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |