Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760930 | 0.89 | UPP1 (0.38) | HTTUPP1 | |
| SCHEMBL8760861 | 0.88 | GAA (0.32) | HTTPNPGAAUPP1 | |
| SCHEMBL8760255 | 0.86 | UPP1 (0.40) | PNPUPP1 | |
| SCHEMBL8760191 | 0.84 | PNP (0.33) | HTTPNP | |
| SCHEMBL9016439 | 0.79 | HTT (0.33) | HTTPNPGAAUPP1MAPT | |
| SCHEMBL8760134 | 0.77 | UPP1 (0.38) | PNPUPP1 | |
| SCHEMBL8760090 | 0.75 | UPP1 (0.49) | UPP1 | |
| SCHEMBL2036799 | 0.75 | UPP1 (0.39) | HTTPNPGAAUPP1MAPT | |
| SCHEMBL7213426 | 0.74 | SIRT2 (0.40) | GAAMAPT | |
| SCHEMBL8760050 | 0.73 | UPP1 (0.35) | HTTPNPUPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | claimed |
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |