Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097240 | 0.74 | TSHR (0.43) | ESR1CYP1A2MEN1KMT2ATSHR | |
| SCHEMBL39946 | 0.73 | ESR1 (0.44) | ESR1S1PR1CYP1A2MEN1KMT2A | |
| Benzene SCHEMBL27985319 | 0.73 | ESR1 (0.44) | ESR1S1PR1CYP1A2MEN1KMT2A | |
| SCHEMBL9818045 | 0.73 | ESR1 (0.44) | ESR1S1PR1CYP1A2MEN1KMT2A | |
| SCHEMBL1257194 | 0.72 | CA12 (0.42) | ESR1S1PR1CYP1A2MEN1KMT2A | |
| Water SCHEMBL10786878 | 0.72 | ESR1 (0.43) | ESR1S1PR1CYP1A2MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28398668 | 0.72 | ESR1 (0.43) | ESR1S1PR1CYP1A2MEN1KMT2A | |
| SCHEMBL83762 | 0.72 | CHKA (0.46) | ESR1S1PR1CYP1A2MEN1KMT2A | |
| SCHEMBL11032897 | 0.72 | CHKA (0.46) | ESR1S1PR1CYP1A2MEN1KMT2A | |
| Methane SCHEMBL27634949 | 0.72 | ESR1 (0.43) | ESR1S1PR1CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578185-B1 | 1-aza-2-silacyclobutane compounds and method for their preparation | DOW CORNING KK (JP) | 1997-09-17 | — | — | EP | disclosed |
| EP-0578186-B1 | Method for the preparation of 1-aza-2-silacyclopentane compounds | DOW CORNING KK (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-5281737-A | 1-aza-2-silacyclobutane compounds and method for their preparation | DOW CORNING JAPAN, LTD. (JP) | 1994-01-25 | — | — | US | disclosed |
| US-5281736-A | Method for the preparation of 1-aza-2-silacyclopentane compounds | DOW CORNING JAPAN, LTD. (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0578186-A1 | Method for the preparation of 1-AZA-2-silacyclopentane compounds | DOW CORNING JAPAN, LTD. (JP) | 1994-01-12 | — | — | EP | disclosed |
| EP-0578185-A1 | 1-AZA-2-silacyclobutane compounds and method for their preparation | DOW CORNING JAPAN, LTD. (JP) | 1994-01-12 | — | — | EP | disclosed |