Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647482 | 0.82 | TP53 (0.40) | TSHRALDH1A1GLACHRM2HTR1A | |
| SCHEMBL11099248 | 0.77 | TSHR (0.50) | TSHRALDH1A1GLASLC6A2SLC6A4 | |
| SCHEMBL19985070 | 0.76 | TSHR (0.36) | TSHRALDH1A1GLAMEN1KMT2A | |
| SCHEMBL8760943 | 0.74 | ESR1 (0.38) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1276854 | 0.69 | KMT2A (0.40) | TSHRALDH1A1GLAMEN1KMT2A | |
| SCHEMBL1276853 | 0.69 | KMT2A (0.40) | TSHRALDH1A1GLAMEN1KMT2A | |
| SCHEMBL409370 | 0.69 | NR3C2 (0.57) | TSHRALDH1A1GLACHRM2HTR1A | |
| SCHEMBL6860839 | 0.69 | TSHR (0.50) | TSHRALDH1A1GLAMEN1KMT2A | |
| Diethylaniline SCHEMBL17594 | 0.69 | TSHR (0.70) | TSHRALDH1A1GLAMEN1KMT2A | |
| Diethylaniline SCHEMBL9000098 | 0.69 | TSHR (0.70) | TSHRALDH1A1GLAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112434-A2 | Hydrogen bearing silyl carbamates | UNION CARBIDE CORPORATION (US) | 1984-07-04 | — | — | EP | disclosed |
| US-4400526-A | Hydrogen bearing silyl carbamates | UNION CARBIDE CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |