Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HBB | P68871 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TK1 | P04183 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760981 | 0.80 | MEN1 (0.49) | MEN1KMT2AHBBBLMMAPK1 | |
| SCHEMBL6833582 | 0.80 | MEN1 (0.47) | MEN1KMT2AHBBBLMMAPK1 | |
| SCHEMBL6266779 | 0.72 | TK1 (0.58) | MEN1KMT2AHBBBLMALDH1A1 | |
| SCHEMBL3857910 | 0.72 | HPRT1 (0.53) | MEN1KMT2AHBBBLMALDH1A1 | |
| SCHEMBL7627167 | 0.72 | PNP (0.58) | MEN1KMT2AHBBBLMMAPK1 | |
| SCHEMBL3857914 | 0.72 | HPRT1 (0.53) | PNPHPRT1 | |
| SCHEMBL6834577 | 0.70 | PNP (0.56) | MEN1KMT2AHBBBLMMAPK1 | |
| SCHEMBL6271393 | 0.70 | TK1 (0.58) | MEN1KMT2AHBBBLMMAPK1 | |
| SCHEMBL6265535 | 0.70 | TK1 (0.61) | MEN1KMT2AHBBBLMALDH1A1 | |
| SCHEMBL8760975 | 0.70 | PNP (0.45) | MEN1KMT2AHBBBLMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701562-B1 | UNSATURATED PHOSPHONATES DERIVATIVES OF PURINES AND PYRIMIDINES | MERRELL PHARMA INC (US) | 1997-06-18 | — | — | EP | claimed |
| EP-0701562-B1 | UNSATURATED PHOSPHONATES DERIVATIVES OF PURINES AND PYRIMIDINES | MERRELL PHARMA INC (US) | 1997-06-18 | — | — | EP | disclosed |