⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263794 | 0.67 | — | — | |
| SCHEMBL9471068 | 0.65 | — | — | |
| SCHEMBL8313015 | 0.64 | — | — | |
| SCHEMBL179958 | 0.63 | — | — | |
| SCHEMBL5005529 | 0.63 | — | — | |
| SCHEMBL2144119 | 0.63 | — | — | |
| SCHEMBL25427427 | 0.60 | — | — | |
| SCHEMBL17138329 | 0.60 | — | — | |
| SCHEMBL29145 | 0.60 | — | — | |
| SCHEMBL20873161 | 0.60 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566113-B | Macrocyclic compounds and uses thereof | 哈佛大学的校长及成员们 | 2024-01-09 | — | — | CN | disclosed |
| CN-104302358-B | The assimilation compound of isoquinolin 1 and their therapeutical uses of 3 aryl 5 substitution | 癌症研究协会:皇家癌症医院 | 2017-12-05 | — | — | CN | disclosed |
| CN-106986832-A | Vegfr3 inhibitor | 癌症治疗合作研究中心有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-104011046-B | Aminopyrimidine kinase inhibitors | 嘉世高制药公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104736533-B | Vegfr3 inhibitor | 癌症治疗合作研究中心有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-105452257-A | Novel fused pyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO LTD | 2016-03-30 | — | — | CN | disclosed |
| CN-101198590-B | pyridine derivative and pyrimidine derivative (3) | EISAI R&D MAN CO LTD | 2012-05-09 | — | — | CN | disclosed |
| CN-101605761-A | Pyridine derivative or pyrimidine derivative exhibiting excellent cell growth inhibitory effect and antitumor effect on HGFR gene-amplified cell line | EISAI R&D MAN CO LTD (JP) | 2009-12-16 | — | — | CN | disclosed |
| CN-100567270-C | Sulfone amide derivative | BANYU PHARMA CO LTD (JP) | 2009-12-09 | — | — | CN | disclosed |
| CN-101516890-A | Diaryl ketimine derivative | BANYU PHARMA CO LTD (JP) | 2009-08-26 | — | — | CN | disclosed |
| CN-1930126-A | Pyridone Derivatives | BANYU PHARMA CO LTD (JP) | 2007-03-14 | — | — | CN | disclosed |
| CN-1922155-A | Novel Sulfonamide Derivatives | BANYU PHARMA CO LTD (JP) | 2007-02-28 | — | — | CN | disclosed |
| CN-1835950-A | Imidazopyridine derivatives | BANYU PHARMA CO LTD (JP) | 2006-09-20 | — | — | CN | disclosed |
| CN-1812981-A | Heteroaryloxy nitrogenous saturated heterocyclic derivative | BANYU PHARMA CO LTD (JP) | 2006-08-02 | — | — | CN | disclosed |
| CN-1791594-A | 2-aminoquinoline derivatives | BANYU PHARMA CO LTD (JP) | 2006-06-21 | — | — | CN | disclosed |
| CN-1188471-A | 1,4-disubstituted piepridine derivatives | BANYU PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |
| EP-0775144-A1 | 6 BETA-SUBSTITUTED PENICILLANIC ACIDS AS BETA-LACTAMASE INHIBITORS | SYNPHAR LABORATORIES INC. (CA) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004285-A1 | 6β-SUBSTITUTED PENICILLANIC ACIDS AS β-LACTAMASE INHIBITORS | SYNPHAR LABORATORIES, INC. (US) | 1996-02-15 | — | — | WO | disclosed |
| US-5464616-A | Antibiotic enzyme inhibitors and kits | SYNPHAR LABORATORIES, IND. (CA) | 1995-11-07 | — | — | US | disclosed |
| US-5143914-A | 2-heteroarylphenyl-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |