SCHEMBL8761209

SCHEMBL8761209

O=C1C=C(C(Cl)(Cl)Cl)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Anhydride SCHEMBL27833266 0.63 HSP90AA1 (0.32)
SCHEMBL9938699 0.60 ALDH1A1 (0.38)
SCHEMBL1205159 0.60
SCHEMBL22654549 0.60
SCHEMBL10781014 0.58 ALOX15 (0.33)
Maleic Anhydride SCHEMBL28565363 0.56
SCHEMBL21661924 0.55
SCHEMBL325566 0.53
SCHEMBL22654552 0.53 MAPT (0.32)
Maleic Anhydride SCHEMBL11617551 0.52 HSP90AA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563013-B1 N-substituted chitosane derivatives, process for preparing them and their use CIBA GEIGY AG (CH) 1997-04-23 EP disclosed
EP-0563013-A2 N-substituted chitosane derivatives, process for preparing them and their use CIBA-GEIGY AG (CH) 1993-09-29 EP disclosed
EP-0375611-B1 ENANTIOMERIC SILANES, MODIFIED SUPPORT AND ITS USE CIBA-GEIGY AG (CH) 1993-04-07 EP disclosed
EP-0376883-B1 ENANTIOMERIC SILANES, MODIFIED SUPPORT AND ITS USE CIBA-GEIGY AG (CH) 1993-04-07 EP disclosed
EP-0376883-A1 Enantiomeric silanes, modified support and its use CIBA-GEIGY AG (CH) 1990-07-04 EP disclosed
EP-0375611-A1 Enantiomeric silanes, modified support and its use CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed