Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876121 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTMAPK1ABCG2 | |
| SCHEMBL875237 | 0.83 | MEN1 (0.33) | ALDH1A1LMNAMAPTABCG2MTNR1A | |
| SCHEMBL875239 | 0.83 | MEN1 (0.33) | ALDH1A1LMNAMAPTABCG2MTNR1A | |
| SCHEMBL19320914 | 0.79 | PARP10 (0.44) | MTNR1AMEN1KMT2APARP10NCEH1 | |
| SCHEMBL4575100 | 0.77 | MEN1 (0.38) | ALDH1A1ABCG2HTTMTNR1AKDM4E | |
| SCHEMBL19325982 | 0.77 | PARP10 (0.46) | ALDH1A1POLBMTNR1AKDM4ECYP1A2 | |
| SCHEMBL28189392 | 0.77 | MAPK8 (0.42) | ALDH1A1MTNR1AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL366864 | 0.76 | MTNR1A (0.37) | ALDH1A1ABCG2HTTMTNR1AKDM4E | |
| SCHEMBL3936169 | 0.76 | MEN1 (0.40) | ALDH1A1ABCG2HTTMTNR1AKDM4E | |
| SCHEMBL28000844 | 0.75 | MTNR1A (0.42) | ALDH1A1MTNR1AKDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619189-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038851-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | PFIZER INC. (US) | 2012-03-29 | — | — | WO | claimed |
| EP-2619189-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038851-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | PFIZER INC. (US) | 2012-03-29 | — | — | WO | disclosed |