Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312910 | 0.92 | TDP1 (0.81) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL6530665 | 0.89 | RAB9A (0.56) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL27395893 | 0.87 | TDP1 (0.69) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL181934 | 0.87 | TDP1 (0.73) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL28152411 | 0.86 | TDP1 (0.67) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL4852019 | 0.85 | KMT2A (0.76) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL6282770 | 0.84 | KMT2A (0.81) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL10917971 | 0.84 | TDP1 (0.69) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL6163969 | 0.84 | TDP1 (0.69) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL11985700 | 0.84 | TDP1 (0.69) | TDP1KMT2ASLC6A2SLC6A3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020247701-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-10 | — | — | WO | disclosed |
| EP-0562824-B1 | Thermal recording material | FUJI PHOTO FILM CO LTD (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5464804-A | Heat sensitive color layer with electron donor, colorless dye is black color aminofluoran, amino compound and isocyanate compound | FUJI PHOTO FILM CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5288688-A | Comprising electron-donating colorless dye, isocyanate and amino compounds; antifogging, discoloration inhibition, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0562824-A2 | Thermal recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |