Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312910 | 0.95 | TDP1 (0.81) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL11985700 | 0.90 | TDP1 (0.69) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL312211 | 0.89 | KMT2A (0.72) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL9266925 | 0.89 | KMT2A (0.72) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL29079463 | 0.89 | ALDH1A1 (0.70) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| Benzyl Benzoate SCHEMBL8359694 | 0.87 | KMT2A (0.89) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL27510637 | 0.87 | LMNA (0.56) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL6282770 | 0.87 | KMT2A (0.81) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL15534582 | 0.87 | RAB9A (0.72) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL6001946 | 0.87 | KMT2A (0.64) | TDP1KMT2ASLC6A2SLC6A3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025109097-A2 | NOVEL NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2025-05-30 | — | — | WO | disclosed |
| US-20250171419-A1 | NOVEL NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2025-05-29 | — | — | US | disclosed |
| EP-3395814-B1 | INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR | BLUEPRINT MEDICINES CORP (US) | 2022-04-06 | — | — | EP | disclosed |
| US-20210347756-A1 | INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR | BLUEPRINT MEDICINES CORPORATION | 2021-11-11 | — | — | US | disclosed |
| US-10875837-B2 | Inhibitors of the fibroblast growth factor receptor | BLUEPRINT MEDICINES CORPORATION (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200109127-A1 | INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR | BLUEPRINT MEDICINES CORPORATION (US) | 2020-04-09 | — | — | US | disclosed |
| US-10221154-B2 | Inhibitors of the fibroblast growth factor receptor | BLUEPRINT MEDICINES CORPORATION (US) | 2019-03-05 | — | — | US | disclosed |
| US-9873613-B2 | Nano or macro material functionalization and self assembled construction mediated by tris(trimethylsilyl)silane | FUNCTIONALIZE, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20150274674-A1 | PYRAZOLE OR TRIAZOLE COMPOUNDS AND THEIR USE FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING SOMATIC MUTATION-RELATED DISEASES | PTC THERAPEUTICS, INC. (US) | 2015-10-01 | — | — | US | disclosed |
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| WO-1994019320-A1 | AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LIMITED (GB) | 1994-09-01 | — | — | WO | disclosed |
| US-5003030-A | Thermoplastic wholly aromatic copolyimide ester and process for producing the same | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1991-03-26 | — | — | US | disclosed |
| EP-0342652-A2 | Thermoplastic wholly aromatic copolyimide ester and process for producing the same | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |
| EP-0055275-B1 | POLYARYLENE SULPHIDE COMPOSITIONS | THE GLACIER METAL COMPANY LIMITED (GB) | 1985-11-27 | — | — | EP | disclosed |
| EP-0055273-B1 | POLYARYLENE SULPHIDE COMPOSITIONS | THE GLACIER METAL COMPANY LIMITED (GB) | 1985-11-27 | — | — | EP | disclosed |
| EP-0055723-B1 | METHOD OF APPLYING A COATING OF POLYARYLENE SULPHIDE TO A COOKING UTENSIL | THE GLACIER METAL COMPANY LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |
| US-4457924-A | PENICILLINS, OXAPENICILLINS, BETA-LACTAMASE INHIBITORS | PFIZER, INC. (US) | 1984-07-03 | — | — | US | disclosed |
| US-4421795-A | Method of applying a coating of polyarylene sulphide to a cooking utensil | THE GLACIER METAL COMPANY LIMITED (GB) | 1983-12-20 | — | — | US | disclosed |
| US-4405740-A | Polyarylene sulphide compositions | THE GLACIER METAL COMPANY LIMITED (GB) | 1983-09-20 | — | — | US | disclosed |
| US-4383069-A | Polyarylene sulphide compositions | THE GLACIER METAL COMPANY LIMITED (GB) | 1983-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200109127-A1 | INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR | FGFR4, FGFR1, FGFR2 | TDP1 2360/4885KMT2A 3129/4885SLC6A2 4771/4885 |
| US-20210347756-A1 | INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR | FGFR4, FGFR1, FGFR2 | TDP1 2360/4885KMT2A 3129/4885SLC6A2 4771/4885 |
| US-10875837-B2 | Inhibitors of the fibroblast growth factor receptor | FGFR4, FGFR1, FGFR2 | TDP1 2360/4885KMT2A 3129/4885SLC6A2 4771/4885 |
| US-20150274674-A1 | PYRAZOLE OR TRIAZOLE COMPOUNDS AND THEIR USE FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING SOMATIC MUTATION-RELATED DISEASES | UPF1, RNMT, VHL | TDP1 189/4885KMT2A 1501/4885SLC6A2 4607/4885 |
| US-20250171419-A1 | NOVEL NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF | NAMPT, NAPRT, NNMT | TDP1 2183/4885KMT2A 374/4885SLC6A2 237/4885 |
| US-10221154-B2 | Inhibitors of the fibroblast growth factor receptor | FGFR4, FGFR1, FGFR2 | TDP1 2360/4885KMT2A 3129/4885SLC6A2 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.