Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278196 | 0.94 | TSHR (0.64) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL14243890 | 0.88 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL6054010 | 0.88 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Ethylene Glycol SCHEMBL36465 | 0.87 | TSHR (0.81) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL2802784 | 0.83 | — | — | |
| SCHEMBL9125539 | 0.83 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL3220127 | 0.82 | TSHR (0.72) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL17147918 | 0.82 | TSHR (0.65) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Ethylene Glycol SCHEMBL18525394 | 0.81 | TSHR (0.71) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Ethylene Glycol SCHEMBL8650028 | 0.81 | TSHR (0.95) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567214-B1 | Co-polymers | ICI PLC (GB) | 1997-04-23 | — | — | EP | claimed |
| EP-0567214-A1 | Co-polymers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-27 | — | — | EP | claimed |