Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657606 | 0.77 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL9621989 | 0.76 | POLB (0.60) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL8761633 | 0.73 | MAPT (0.43) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL12513507 | 0.72 | KMT2A (0.65) | KMT2AMEN1ALDH1A1MAPTGFER | |
| SCHEMBL18087689 | 0.71 | USP2 (0.46) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL11663104 | 0.71 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTGFER | |
| SCHEMBL1408147 | 0.70 | MEN1 (0.42) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL9186359 | 0.70 | KCNH2 (0.46) | KMT2AMEN1KDM4E | |
| SCHEMBL9180518 | 0.70 | KMT2A (0.72) | KMT2AMEN1ALDH1A1MAPTGFER | |
| SCHEMBL15055497 | 0.70 | SMN1; SMN2 (0.53) | ALDH1A1MAPTNPSR1SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703215-A | SOLID WATER SOLUBLE DYE CONTAINING ELECTROPHILIC AND NUCLEOPHILIC GROUPS, WHICH WHEN HEATED AND/OR BASIFIED CAUSES FORMATION OF COVALENT BONDS BETWEEN SAID GROUPS ON DIFFERENT MOLECULES | ZENECA LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |
| EP-0639237-B1 | DYES, THEIR PREPARATION AND USE IN THE COLORATION OF SUBSTRATES | BASF AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5474580-A | Applying to substrate a mixture of water and water soluble dye containing nucleophilic and electrophilic group, heating or basifying to cause molecule of dyes to join together | ZENECA LIMITED (GB) | 1995-12-12 | — | — | US | disclosed |
| EP-0639237-A1 | DYES, THEIR PREPARATION AND USE IN THE COLORATION OF SUBSTRATES. | ZENECA LTD (GB) | 1995-02-22 | — | — | EP | disclosed |
| WO-1994012717-A1 | DYES, THEIR PREPARATION AND USE IN THE COLORATION OF SUBSTRATES | ZENECA LIMITED (GB) | 1994-06-09 | — | — | WO | disclosed |