Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761454 | 0.91 | KMT2A (0.49) | MAPTNPSR1GAAALOX12CRHBP | |
| SCHEMBL8761649 | 0.73 | KMT2A (0.44) | MAPTNPSR1GAAHTTALDH1A1 | |
| SCHEMBL11429169 | 0.73 | ALDH1A1 (0.47) | MAPTGAAALDH1A1TP53TYR | |
| SCHEMBL1408147 | 0.73 | MEN1 (0.42) | MAPTNPSR1GAAALDH1A1TSHR | |
| SCHEMBL3911693 | 0.73 | KMT2A (0.62) | MAPTGAAHTTALDH1A1KMT2A | |
| SCHEMBL9621989 | 0.72 | POLB (0.60) | MAPTNPSR1GAAHTTALDH1A1 | |
| SCHEMBL5533037 | 0.71 | KMT2A (0.56) | TSHRKMT2ASMN1; SMN2LMNA | |
| SCHEMBL5928136 | 0.71 | OPRM1 (0.42) | MAPTNPSR1ALDH1A1TSHRKMT2A | |
| SCHEMBL17956753 | 0.70 | TRPV1 (0.58) | TSHRKMT2ASMN1; SMN2LMNA | |
| SCHEMBL5378450 | 0.70 | OPRM1 (0.41) | TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703215-A | SOLID WATER SOLUBLE DYE CONTAINING ELECTROPHILIC AND NUCLEOPHILIC GROUPS, WHICH WHEN HEATED AND/OR BASIFIED CAUSES FORMATION OF COVALENT BONDS BETWEEN SAID GROUPS ON DIFFERENT MOLECULES | ZENECA LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |
| EP-0639237-B1 | DYES, THEIR PREPARATION AND USE IN THE COLORATION OF SUBSTRATES | BASF AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5474580-A | Applying to substrate a mixture of water and water soluble dye containing nucleophilic and electrophilic group, heating or basifying to cause molecule of dyes to join together | ZENECA LIMITED (GB) | 1995-12-12 | — | — | US | disclosed |
| EP-0639237-A1 | DYES, THEIR PREPARATION AND USE IN THE COLORATION OF SUBSTRATES. | ZENECA LTD (GB) | 1995-02-22 | — | — | EP | disclosed |
| WO-1994012717-A1 | DYES, THEIR PREPARATION AND USE IN THE COLORATION OF SUBSTRATES | ZENECA LIMITED (GB) | 1994-06-09 | — | — | WO | disclosed |