SCHEMBL8762131

SCHEMBL8762131

O=S(=O)(Nc1ccccc1)c1cccc(-c2ccccc2)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PFKFB3 Q16875 1/20 0.72
PGR P06401 2/20 0.69
IL1RN P18510 1/20 0.68
KEAP1 Q14145 1/20 0.68
ERAP1 Q9NZ08 1/20 0.68
POLB P06746 1/20 0.67
MEN1 O00255 2/20 0.63
PKM P14618 2/20 0.63
KMT2A Q03164 2/20 0.63
ALDH1A1 P00352 1/20 0.63
PFKFB4 Q16877 1/20 0.62
PTGES2 Q9H7Z7 1/20 0.60
HDAC6 Q9UBN7 3/20 0.58
HTR6 P50406 2/20 0.58
HDAC2 Q92769 2/20 0.58
HDAC8 Q9BY41 2/20 0.58
KDM1A O60341 1/20 0.56
UQCRB P14927 2/20 0.56
MAPT P10636 1/20 0.56
MAPK1 P28482 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8278220 0.91 PGR (0.62) PFKFB3PGRIL1RNKEAP1ERAP1
SCHEMBL8081768 0.88 KEAP1 (0.79) PGRIL1RNKEAP1ERAP1POLB
SCHEMBL787677 0.85 PFKFB3 (1.00) PFKFB3POLBMEN1KMT2APFKFB4
SCHEMBL812691 0.84 POLB (0.67) PFKFB3PGRIL1RNKEAP1ERAP1
SCHEMBL13480185 0.82 KMT2A (0.77) PGRIL1RNKEAP1ERAP1POLB
SCHEMBL812677 0.82 KMT2A (0.77) PGRIL1RNKEAP1ERAP1POLB
SCHEMBL14044734 0.82 CA12 (0.74) PGRERAP1MEN1PKMKMT2A
SCHEMBL25031372 0.82 KEAP1 (1.00) PGRIL1RNKEAP1ERAP1POLB
Phenyl(Phenylsulfonyl)Amine SCHEMBL114765 0.82 KEAP1 (1.00) PGRIL1RNKEAP1ERAP1POLB
SCHEMBL7805558 0.81 IDH2 (0.61) PFKFB3PGRMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0562824-B1 Thermal recording material FUJI PHOTO FILM CO LTD (JP) 1997-06-11 EP disclosed
US-5464804-A Heat sensitive color layer with electron donor, colorless dye is black color aminofluoran, amino compound and isocyanate compound FUJI PHOTO FILM CO., LTD. (JP) 1995-11-07 US disclosed
US-5288688-A Comprising electron-donating colorless dye, isocyanate and amino compounds; antifogging, discoloration inhibition, storage stability FUJI PHOTO FILM CO., LTD. (JP) 1994-02-22 US disclosed
EP-0562824-A2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1993-09-29 EP disclosed