SCHEMBL8762164

SCHEMBL8762164

COC(=O)c1ccc(N(C)C)cc1C(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
PDK2 Q15119 1/20 0.47
PDK4 Q16654 1/20 0.47
ALDH1A1 P00352 4/20 0.45
TSHR P16473 4/20 0.45
GAA P10253 3/20 0.45
HSD17B10 Q99714 3/20 0.45
KDM4E B2RXH2 3/20 0.45
HPGD P15428 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
MAPK1 P28482 2/20 0.45
NPC1 O15118 2/20 0.45
MAPT P10636 5/20 0.44
GLA P06280 1/20 0.44
CASP1 P29466 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19874811 0.91 SLC16A3 (0.44) CA12CA1CA2CA7CA9
SCHEMBL18015088 0.87 KDM4E (0.47) CA12CA1CA2CA7CA9
SCHEMBL30966775 0.87 KDM4E (0.47) CA12CA1CA2CA7CA9
SCHEMBL17212684 0.87 LMNA (0.57) ALDH1A1TSHRGAAHSD17B10KDM4E
SCHEMBL4300593 0.87 ALDH1A1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL3165135 0.85 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL21775704 0.85 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL25247275 0.84 ALDH1A1 (0.43) CA12CA1CA2CA7CA9
SCHEMBL1129609 0.84 ALDH1A1 (0.58) ALDH1A1TSHRGAAHSD17B10KDM4E
SCHEMBL22749397 0.84 ALDH1A1 (0.62) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11529760-B2 Polymeric materials and articles manufactured there from THE PROCTER & GAMBLE COMPANY (US) 2022-12-20 US disclosed
US-11040812-B2 Water soluble containers and methods of making them THE PROCTER & GAMBLE COMPANY (US) 2021-06-22 US disclosed
US-20200270038-A1 WATER SOLUBLE CONTAINERS AND METHODS OF MAKING THEM PROCTER & GAMBLE (US) 2020-08-27 US disclosed
US-10703549-B2 Water soluble containers and methods of making them THE PROCTER AND GAMBLE COMPANY (US) 2020-07-07 US disclosed
EP-3645697-A1 WATER SOLUBLE CONTAINERS AND METHODS OF MAKING THEM The Procter and Gamble Company (US) 2020-05-06 EP disclosed
US-20200086551-A1 Polymeric Materials and Articles Manufactured There From PROCTER & GAMBLE (US) 2020-03-19 US disclosed
US-10543639-B2 Method for manufacturing a three-dimensional object THE PROCTER & GAMBLE COMPANY (US) 2020-01-28 US disclosed
CN-110730816-A Water-soluble container and method for producing same 宝洁公司 2020-01-24 CN disclosed
EP-3500231-A1 POLYMERIC MATERIALS AND ARTICLES MANUFACTURED THERE FROM The Procter and Gamble Company (US) 2019-06-26 EP disclosed
US-20190002172-A1 Water soluble containers and methods of making them VIRGINIA TECH INTELLECTUAL PROPERTIES (US) 2019-01-03 US disclosed
WO-2019006234-A1 WATER SOLUBLE CONTAINERS AND METHODS OF MAKING THEM THE PROCTER & GAMBLE COMPANY (US) 2019-01-03 WO disclosed
US-20180050487-A1 Polymeric Materials and Articles Manufactured There From VIRGINIA TECH INTELLECTUAL PROPERTIES INC (US) 2018-02-22 US disclosed
WO-2018034849-A1 POLYMERIC MATERIALS AND ARTICLES MANUFACTURED THERE FROM THE PROCTER & GAMBLE COMPANY (US) 2018-02-22 WO disclosed
US-5698580-A TREATING DISEASES CAUSED BY RESPIRATORY SYNCYTIAL VIRUS RATIONAL DRUG DESIGN LABORATORIES (JP) 1997-12-16 US disclosed
EP-0770609-A1 ANTIVIRAL AGENT CONTAINING BENZODITHIIN DERIVATIVE AS ACTIVE INGREDIENT Rational Drug Design Laboratories (JP) 1997-05-02 EP disclosed
US-4134813-A THIOCHROMANONES, AMINE BASF AKTIENGESELLSCHAFT (DE) 1979-01-16 US disclosed
US-4002664-A Manufacture of dimethylaminobenzenecarboxylic acid esters BASF AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11529760-B2 Polymeric materials and articles manufactured there from ALG3, CD68, VCL CA12 1322/4885CA1 922/4885CA2 1773/4885
US-20200086551-A1 Polymeric Materials and Articles Manufactured There From ALG3, CD68, VCL CA12 1322/4885CA1 922/4885CA2 1773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.