Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624650 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL8762228 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL8762809 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL7946933 | 0.81 | HTR6 (0.31) | — | |
| Hydrochloric Acid SCHEMBL397941 | 0.80 | HTR6 (0.30) | — | |
| Hydrochloric Acid SCHEMBL715370 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL9009994 | 0.77 | — | — | |
| SCHEMBL7033952 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6905921 | 0.75 | — | — | |
| SCHEMBL7034305 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610851-B1 | Process for preparing cyclo-olefin copolymers | HOECHST AG (DE) | 1997-05-07 | — | — | EP | claimed |
| US-5602219-A | POLYMERIZING WITH ETHYLENE, AN ACYCLIC OLEFIN AND /OR A MONOCYCLIC OLEFIN IN THE PRESENCE OF A CATALYST SYSTEM COMPRISING A COCATALYST AND AN ASYMMETRICAL METALLOCENE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | claimed |
| CN-1101052-A | Preparation of cycloolefincopolymer | HOECHST AG (DE) | 1995-04-05 | — | — | CN | claimed |
| US-5602219-A | POLYMERIZING WITH ETHYLENE, AN ACYCLIC OLEFIN AND /OR A MONOCYCLIC OLEFIN IN THE PRESENCE OF A CATALYST SYSTEM COMPRISING A COCATALYST AND AN ASYMMETRICAL METALLOCENE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| CN-1101052-A | Preparation of cycloolefincopolymer | HOECHST AG (DE) | 1995-04-05 | — | — | CN | disclosed |