Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5624457 | 0.82 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NISCHMTORADK | |
| SCHEMBL1983146 | 0.79 | NISCH (0.45) | ALDH1A1NISCHMTORADKTAAR1 | |
| SCHEMBL29683638 | 0.78 | — | — | |
| SCHEMBL8579331 | 0.78 | — | — | |
| SCHEMBL187790 | 0.78 | — | — | |
| SCHEMBL8579336 | 0.78 | — | — | |
| SCHEMBL6368310 | 0.78 | — | — | |
| SCHEMBL1145756 | 0.78 | — | — | |
| SCHEMBL11165626 | 0.76 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5969677 | 0.76 | NISCH (0.48) | ALDH1A1SMN1; SMN2NISCHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296922-A1 | POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI WENNAI THERAPEUTICS CO LTD (CN) | 2025-09-25 | — | — | US | claimed |
| WO-2025021115-A1 | POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海闻耐医药科技有限公司 | 2025-01-30 | — | — | WO | claimed |
| US-5240964-A | Adding piperazine catalyst with imidazole, triazine or amidine compound to create difference in gas evolution between inner and outer parts of plastic liquid | TOKYO SEAT CO., LTD. (JP) | 1993-08-31 | — | — | US | claimed |
| EP-0358377-B1 | BIS IMIDAZOLE ETHERS AS METAL DEACTIVATORS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1993-04-28 | — | — | EP | claimed |
| US-5141684-A | Using catalyst which creates difference in gas evolution between inner and outer parts of plastic liquid in mold to form high density layer on outer surface | TOKYO SHEET CO., LTD. (JP) | 1992-08-25 | — | — | US | claimed |
| US-5139713-A | One step molding, high density surfaces | TOKYO SHEET CO., LTD. (JP) | 1992-08-18 | — | — | US | claimed |
| US-5011935-A | Imidazole ether compounds | SAN-APRO LIMITED (JP) | 1991-04-30 | — | — | US | claimed |
| JP-4298519-A | — | — | None | — | — | JP | disclosed |
| JP-3033120-A | — | — | None | — | — | JP | disclosed |
| JP-2117665-A | — | — | None | — | — | JP | disclosed |
| JP-2160768-A | — | — | None | — | — | JP | disclosed |
| US-12612383-B2 | Polysubstituted pyrrolidine derivative, preparation method therefor and use thereof | SHANGHAI WENNAI THERAPEUTICS CO., LTD. (CN) | 2026-04-28 | — | — | US | disclosed |
| US-20250296922-A1 | POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI WENNAI THERAPEUTICS CO LTD (CN) | 2025-09-25 | — | — | US | disclosed |
| US-4312880-A | COMBATING PHYTOPATHOGENS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| EP-0040366-A1 | Imidazolyl-vinyl ketones and carbinols, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-11-25 | — | — | EP | disclosed |
| EP-0023614-A1 | Antimycotic compositions containing imidazolylenol ethers, their preparation and their use | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
| EP-0023651-A1 | Imidazolyl-enol ethers, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
| US-4224452-A | HYDROLYSIS | ETHYL CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| US-4224452-A | HYDROLYSIS | ETHYL CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| JP-H00333120-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250296922-A1 | POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SCN8A, SCN11A, TRPV1 | ALDH1A1 2001/4885SMN1; SMN2 1522/4885NISCH 426/4885 |
| US-12612383-B2 | Polysubstituted pyrrolidine derivative, preparation method therefor and use thereof | SCN8A, SCN11A, TRPV1 | ALDH1A1 2204/4885SMN1; SMN2 1714/4885NISCH 982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.