SCHEMBL1983146

SCHEMBL1983146

c1ccc(Oc2ncc[nH]2)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.45
MTOR P42345 1/20 0.45
ADK P55263 1/20 0.45
LTA4H P09960 8/20 0.44
TSHR P16473 1/20 0.44
TRPA1 O75762 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
NPC1 O15118 1/20 0.38
SCN4A P35499 1/20 0.38
RAB9A P51151 1/20 0.38
KDM4C Q9H3R0 1/20 0.37
HAO1 Q9UJM8 1/20 0.37
TTBK1 Q5TCY1 1/20 0.36
TTBK2 Q6IQ55 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
NR1H2 P55055 1/20 0.35
BAX Q07812 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5969677 0.80 NISCH (0.48) NISCHNPC1RAB9ATTBK1TTBK2
SCHEMBL4722556 0.80 ALDH1A1 (0.31) NISCHMTORADKALDH1A1
SCHEMBL876246 0.79 ALDH1A1 (0.43) NISCHMTORADKTAAR1ALDH1A1
SCHEMBL28575785 0.79 KCNA3 (0.48) NISCHMTORADKTSHRTAAR1
SCHEMBL943191 0.76 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL2221480 0.74 F2 (0.58)
SCHEMBL5151126 0.73 NISCH (0.69) NISCHMTORADKLTA4HTSHR
SCHEMBL6947510 0.72 NISCH (0.41) NISCHNPC1RAB9ATTBK1TTBK2
SCHEMBL4264926 0.72 TAAR1 (0.52) NISCHMTORADKLTA4HTSHR
SCHEMBL4722554 0.72 MTOR (0.35) NISCHMTORADKTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1303791-B1 MULTICOLOR IMAGING USING MULTIPHOTON PHOTOCHEMICAL PROCESSES 3M INNOVATIVE PROPERTIES CO (US) 2009-08-19 EP claimed
US-7026103-B2 Multicolor imaging using multiphoton photochemical processes 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-04-11 US claimed
US-20030194651-A1 Multicolor imaging using multiphoton photochemical processes 3M INNOVATIVE PROPERTIES COMPANY 2003-10-16 US claimed
EP-1303791-A2 MULTICOLOR IMAGING USING MULTIPHOTON PHOTOCHEMICAL PROCESSES 3M Innovative Properties Company (US) 2003-04-23 EP claimed
WO-2001096952-A2 MULTICOLOR IMAGING USING MULTIPHOTON PHOTOCHEMICAL PROCESSES 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-20 WO claimed
CN-116728973-A Printing apparatus 手持产品公司 2023-09-12 CN disclosed
US-20220411388-A1 SUBSTITUTED IMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS BIAL R&D INVEST S A (PT) 2022-12-29 US disclosed
EP-4031531-A1 SUBSTITUTED IMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS Bial-R&D Investments, S.A. (PT) 2022-07-27 EP disclosed
CN-114787135-A Substituted imidazole carboxamides and their use in the treatment of medical disorders 比亚尔R&D投资股份公司 2022-07-22 CN disclosed
CN-114763033-A Printing apparatus 手持产品公司 2022-07-19 CN disclosed
WO-2021055612-A1 SUBSTITUTED IMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS BIAL-BioTech Investments, Inc. (US) 2021-03-25 WO disclosed
US-9529261-B2 Color-forming composition, color-forming curable composition, lithographic printing plate precursor and plate making method, and color-forming compound FUJIFILM CORPORATION (JP) 2016-12-27 US disclosed
EP-1537142-A1 AKAP18 DELTA, A NOVEL SPLICING VARIANT OF A PROTEIN KINASE A ANCHOR PROTEIN AND THE USE OF THE SAME Forschungsverbund Berlin e.V. (DE) 2005-06-08 EP disclosed
WO-2004022591-A1 AKAP18 DELTA, A NOVEL SPLICING VARIANT OF A PROTEIN KINASE A ANCHOR PROTEIN AND THE USE OF THE SAME FORSCHUNGSVERBUND BERLIN E. V. (DE) 2004-03-18 WO disclosed
EP-0913392-B1 ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS NISSAN CHEMICAL IND LTD (JP) 2003-07-02 EP disclosed
US-5670526-A ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-09-23 US disclosed
EP-0385330-B1 Mixtures of dyestuffs comprising azo compounds on the basis of phenylox diazolyl aniline BASF AG (DE) 1995-05-17 EP disclosed
EP-0385330-A2 Mixtures of dyestuffs comprising azo compounds on the basis of phenylox diazolyl aniline BASF Aktiengesellschaft (DE) 1990-09-05 EP disclosed
US-4891432-A ANTITUMOR AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1990-01-02 US disclosed
US-4207328-A 1-Phenoxy-2-(2,4-dichlorophenyl)-1-imidazol-1-yl-ethan-2-ones and -ols and antimycotic and fungicidal use BAYER AKTIENGESELLSCHAFT (DE) 1980-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411388-A1 SUBSTITUTED IMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS GBA1, GAA, CLN6 NISCH 48/4885MTOR 654/4885ADK 1938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.