Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.50 |
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429252 | 0.85 | MME (0.55) | MMEACEACE2CPA1MMP2 | |
| SCHEMBL8387195 | 0.80 | MME (0.65) | MMEACEACE2CPA1MMP1 | |
| SCHEMBL7374244 | 0.79 | MME (0.57) | MMEACEACE2CPA1MMP1 | |
| SCHEMBL8764745 | 0.79 | ECE1 (0.57) | ACEMMP1 | |
| SCHEMBL8764113 | 0.78 | MME (0.63) | MMEACEACE2CPA1MMP1 | |
| SCHEMBL7384919 | 0.78 | MME (0.63) | MMEACEACE2CPA1MMP1 | |
| SCHEMBL8390537 | 0.78 | MME (0.63) | MMEACEACE2CPA1MMP1 | |
| SCHEMBL8764190 | 0.78 | MME (0.43) | MMEACEACE2CPA1MMP1 | |
| SCHEMBL7344017 | 0.77 | MME (0.55) | MMEACEACE2CPA1MMP1 | |
| SCHEMBL8390276 | 0.77 | MME (0.68) | MMEACEACE2CPA1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784629-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | claimed |
| WO-1996011209-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | claimed |