Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 7/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763014 | 0.78 | MME (0.50) | MMEACECPA1ACE2MMP1 | |
| SCHEMBL8764118 | 0.76 | LTA4H (0.38) | ACEMMP1RENMMP2MMP9 | |
| SCHEMBL7344017 | 0.73 | MME (0.55) | MMEACECPA1ACE2MMP1 | |
| SCHEMBL8764113 | 0.71 | MME (0.63) | MMEACECPA1ACE2MMP1 | |
| SCHEMBL7384919 | 0.71 | MME (0.63) | MMEACECPA1ACE2MMP1 | |
| SCHEMBL8390537 | 0.71 | MME (0.63) | MMEACECPA1ACE2MMP1 | |
| SCHEMBL7382939 | 0.71 | MME (0.61) | MMEACECPA1ACE2MMP1 | |
| SCHEMBL8385738 | 0.71 | MME (0.61) | MMEACECPA1ACE2MMP1 | |
| SCHEMBL7374244 | 0.70 | MME (0.57) | MMEACECPA1ACE2MMP1 | |
| SCHEMBL7594973 | 0.70 | FCER2 (0.46) | MMEACECPA1ACE2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784629-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | claimed |
| WO-1996011209-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | claimed |