SCHEMBL8763136

SCHEMBL8763136

CC(C)(c1ccccc1CCNC=S)c1ccccc1CCNC=S

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.33
CNR1 P21554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763620 0.83 ADH1B (0.36) TAAR1CNR1
SCHEMBL8763253 0.81 TAAR1 (0.38) TAAR1
SCHEMBL10434107 0.77 TAAR1 (0.36) TAAR1
SCHEMBL8763887 0.76 TAAR1 (0.38) TAAR1
SCHEMBL7755750 0.70 TDP1 (0.39)
SCHEMBL8763139 0.68 ESRRG (0.41) TAAR1
SCHEMBL7963483 0.67 NPC1 (0.52) TAAR1
SCHEMBL2909758 0.67 TAAR1 (0.55) TAAR1
SCHEMBL16105766 0.66 GABRA1 (0.48)
SCHEMBL20897169 0.66 IDO1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0349195-B1 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC (US) 1997-05-21 EP disclosed
US-5629394-A ENDCAPPING ADDITION POLYMERS WITH NITROGEN FUNCTIONAL GROUPS WHICH CAN BE FURTHER DERIVATIZED EXXON CHEMICAL PATENTS INC (US) 1997-05-13 US disclosed
US-5444135-A Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously EXXON CHEMICAL PATENTS INC. (US) 1995-08-22 US disclosed
US-5336745-A Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators EXXON CHEMICAL PATENTS INC. (US) 1994-08-09 US disclosed
US-5032653-A Catalysts EXXON CHEMICAL PATENTS, INC. (US) 1991-07-16 US disclosed