Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762629 | 0.90 | CYP2C9 (0.40) | TYRALDH1A1KDM4EHPGDF2R | |
| SCHEMBL9128005 | 0.89 | CA2 (0.42) | TYRALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL8762772 | 0.84 | CA2 (0.41) | TYRALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL19358175 | 0.83 | TYR (0.49) | TYRALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL8762782 | 0.83 | HSPA5 (0.46) | TYRALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL8772295 | 0.82 | HSPA5 (0.50) | TYRALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL28745750 | 0.77 | TYR (0.49) | TYRALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9854608 | 0.76 | PTPN1 (0.36) | TYRALDH1A1LMNACYP2C9HSD17B10 | |
| SCHEMBL8763395 | 0.76 | CNR1 (0.42) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14718247 | 0.76 | HSPA5 (0.43) | TYRALDH1A1HPGDLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605127-B1 | Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules | XEROX CORP (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5401615-A | Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules | XEROX CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0605127-A1 | Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules | XEROX CORPORATION (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0186303-B1 | ELECTROPHOTOGRAPHIC IMAGING MEMBERS | XEROX CORPORATION (US) | 1989-06-07 | — | — | EP | disclosed |
| US-4599286-A | ELECTROGRAPHY | XEROX CORPORATION (US) | 1986-07-08 | — | — | US | disclosed |
| EP-0186303-A1 | Electrophotographic imaging members | XEROX CORPORATION (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4563408-A | ELECTROGRAPHY | XEROX CORPORATION (US) | 1986-01-07 | — | — | US | disclosed |