SCHEMBL8772295

SCHEMBL8772295

CC(C)(C)c1cc(Cc2cc(C(C)(C)C)c(O)c3ccccc23)c2ccccc2c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.50
HMGB1 P09429 1/20 0.50
CXCL12 P48061 1/20 0.50
CYP2C9 P11712 4/20 0.49
CYP2C19 P33261 4/20 0.49
HIF1A Q16665 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
CYP2D6 P10635 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA2 P00918 3/20 0.42
CA1 P00915 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 3/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GAA P10253 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772275 0.92 HSPA5 (0.47) HSPA5HMGB1CXCL12CYP2C9CYP2C19
SCHEMBL9128005 0.89 CA2 (0.42) HSPA5HMGB1CXCL12CYP2C9CYP2C19
SCHEMBL8762782 0.87 HSPA5 (0.46) HSPA5HMGB1CXCL12CYP2C9CYP2C19
SCHEMBL8772290 0.87 KEAP1 (0.45) HSPA5HMGB1CXCL12GAAMEN1
SCHEMBL9817048 0.86 SHBG (0.42) HSPA5HMGB1CXCL12CYP2C9CYP2C19
SCHEMBL8772332 0.85 HSPA5 (0.42) HSPA5HMGB1CXCL12CYP2C9HSD17B10
SCHEMBL8762629 0.84 CYP2C9 (0.40) HSPA5HMGB1CXCL12CYP2C9CYP2C19
SCHEMBL8772364 0.82 HMGB1 (0.37) HSPA5HMGB1CXCL12CYP2C9CYP2C19
SCHEMBL8763524 0.82 TYR (0.40) HSPA5CYP2C9CYP2C19HSD17B10CA2
SCHEMBL8772292 0.81 HSPA5 (0.54) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5409798-A Base layer containing polymerizable compound, photosensitive layer capable of peeling development containing different polymerizable compound, layer-forming polymer, photoinitiator, peeling support layer CANON KABUSHIKI KAISHA (JP) 1995-04-25 US disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
EP-0530674-A1 Plate blank, process for producing printing plate from plate blank, and printing method and apparatus using plate CANON KABUSHIKI KAISHA (JP) 1993-03-10 EP disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
EP-0453317-A2 Image forming medium CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed