SCHEMBL8763544

SCHEMBL8763544

NC1(N)C=c2ccccc2=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30239062 0.71
SCHEMBL10816467 0.71
SCHEMBL13782360 0.68
SCHEMBL5851717 0.68 GSK3B (0.31)
SCHEMBL28746681 0.66 HDAC1 (0.33)
SCHEMBL10875559 0.65 CYP2C9 (0.42)
SCHEMBL3991516 0.60 CYP2A6 (0.31)
SCHEMBL7600 0.60
SCHEMBL28926314 0.60 MAOA (0.33)
SCHEMBL12430552 0.58 ALDH1A1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10584212-B2 Polyamide-imide, raw material salt of polyamide-imide, and production method thereof UNITIKA LTD. (JP) 2020-03-10 US claimed
US-10584212-B2 Polyamide-imide, raw material salt of polyamide-imide, and production method thereof UNITIKA LTD. (JP) 2020-03-10 US disclosed
EP-3281938-B1 METHOD FOR PRODUCING BISIMIDODICARBOXYLIC ACID UNITIKA LTD (JP) 2019-09-18 EP disclosed
US-20180086704-A1 METHOD FOR PRODUCING BISIMIDE DICARBOXYLIC ACID UNITIKA LTD. (JP) 2018-03-29 US disclosed
US-20180072848-A1 POLYAMIDE-IMIDE, RAW MATERIAL SALT OF POLYAMIDE-IMIDE, AND PRODUCTION METHOD THEREOF UNITIKA LTD. (JP) 2018-03-15 US disclosed
EP-3281967-A1 POLYAMIDE-IMIDE, RAW MATERIAL SALT FOR POLYAMIDE-IMIDE, AND METHODS RESPECTIVELY FOR PRODUCING THESE COMPOUNDS Unitika, Ltd. (JP) 2018-02-14 EP disclosed
EP-3281938-A1 METHOD FOR PRODUCING BISIMIDODICARBOXYLIC ACID Unitika Ltd. (JP) 2018-02-14 EP disclosed
CN-107428936-A Polyamidoimide, polyamidoimide raw material salt and their manufacture method 尤尼吉可株式会社 2017-12-01 CN disclosed
EP-0490490-B1 Process for producing bistrimellitic imide MITSUBISHI GAS CHEMICAL CO (JP) 1997-07-16 EP disclosed
US-5182392-A PROCESS FOR PRODUCING BISTRIMELLITIC IMIDE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-01-26 US disclosed
EP-0490490-A1 Process for producing bistrimellitic imide MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-06-17 EP disclosed