Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | C1R | P00736 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474081 | 0.88 | KCNN4 (0.48) | TP53NOTUMC1RELANEMAPK11 | |
| SCHEMBL10475286 | 0.88 | KCNN4 (0.48) | NPC1RAB9ATP53HPGDSMN1; SMN2 | |
| SCHEMBL10473940 | 0.88 | ELANE (0.47) | NPC1RAB9ATP53HPGDSMN1; SMN2 | |
| SCHEMBL10473911 | 0.87 | HPGD (0.41) | NPC1RAB9ATP53HPGDSMN1; SMN2 | |
| SCHEMBL10473917 | 0.87 | NPC1 (0.46) | NPC1RAB9ATP53HPGDSMN1; SMN2 | |
| SCHEMBL10475371 | 0.85 | MAPK11 (0.40) | TP53MAPK11MAPK14KMT2AMAPT | |
| SCHEMBL10475151 | 0.85 | HSD11B1 (0.42) | NPC1RAB9ATP53HPGDSMN1; SMN2 | |
| SCHEMBL10473912 | 0.85 | MAPK11 (0.47) | TP53MAPK11MAPK14 | |
| SCHEMBL8764379 | 0.84 | MAPK14 (0.40) | MAPK11MAPK14MEN1KMT2AMAPT | |
| SCHEMBL10475047 | 0.82 | MAPT (0.41) | NOTUMMAPK11MAPK14MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533276-B1 | Oxa(thia)diazol - and triazol-ones having a miticide and insecticide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-07-30 | — | — | EP | disclosed |
| US-5550140-A | Oxa(thia)diazol- and triazol-ones(thiones) having a miticide and insecticide activity | Ministero Dell `Universita` e Della Ricerca Scientifica e Tecnologica (IT) | 1996-08-27 | — | — | US | disclosed |
| US-5418246-A | Oxa(thia)diazol- and triazol-ones(thiones) having a miticide and insecticide activity | Ministero Dell `Universita` e Della Ricerca Scientifica e Technologica (IT) | 1995-05-23 | — | — | US | disclosed |
| EP-0533276-A1 | Oxa(thia)diazol - and triazol-ones (thiones) having a miticide and insecticide activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-03-24 | — | — | EP | disclosed |