Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | C1R | P00736 | 2/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763552 | 0.85 | NPC1 (0.47) | NOTUMHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL10475125 | 0.85 | HSD11B1 (0.42) | HSD11B1NOTUMHPGDKDM4EALDH1A1 | |
| SCHEMBL10474084 | 0.83 | MAPT (0.42) | NOTUMKDM4EKMT2AMGLLGAA | |
| SCHEMBL10475286 | 0.83 | KCNN4 (0.48) | NOTUMHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL10475368 | 0.81 | MGLL (0.47) | NOTUMHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL10473910 | 0.79 | MGLL (0.40) | HSD11B1NOTUMMGLLPSMB8MAPT | |
| SCHEMBL10473911 | 0.79 | HPGD (0.41) | HSD11B1NOTUMHPGDKDM4EALDH1A1 | |
| SCHEMBL10475055 | 0.78 | MGLL (0.41) | NOTUMKDM4EALDH1A1KMT2AMGLL | |
| SCHEMBL10474201 | 0.78 | KMT2A (0.44) | HSD11B1NOTUMHPGDKDM4EALDH1A1 | |
| SCHEMBL10474081 | 0.77 | KCNN4 (0.48) | NOTUMTP53MAPTC1RELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943583-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-24 | — | — | US | claimed |
| EP-0270061-A2 | Five-membered heterocycles with three heteroatoms, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1988-06-08 | — | — | EP | claimed |
| US-4943583-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-24 | — | — | US | disclosed |
| EP-0270061-A2 | Five-membered heterocycles with three heteroatoms, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1988-06-08 | — | — | EP | disclosed |