Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015910 | 0.82 | ATM (0.59) | ALDH1A1KDM4ENPC1GAAHPGD | |
| SCHEMBL29134888 | 0.82 | ATM (0.59) | ALDH1A1KDM4ENPC1GAAHPGD | |
| SCHEMBL6161452 | 0.81 | PRMT1 (0.59) | ALDH1A1KDM4EGAAHPGDCYP19A1 | |
| SCHEMBL3239227 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KDM4ENPC1GAAHPGD | |
| SCHEMBL8762732 | 0.78 | KMT2A (0.66) | ALDH1A1KDM4ENPC1GAAHPGD | |
| SCHEMBL922755 | 0.78 | CYP19A1 (0.66) | ALDH1A1SMN1; SMN2CYP19A1F2PRSS1 | |
| SCHEMBL2788724 | 0.78 | PRMT1 (0.61) | ALDH1A1KDM4ENPC1GAAHPGD | |
| SCHEMBL1565027 | 0.77 | PRMT1 (0.73) | ALDH1A1KDM4ESMN1; SMN2CYP19A1F2 | |
| SCHEMBL31174173 | 0.77 | PRMT1 (0.73) | ALDH1A1KDM4ESMN1; SMN2CYP19A1F2 | |
| SCHEMBL3932801 | 0.77 | GAA (0.57) | ALDH1A1KDM4ENPC1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770063-A1 | TECHNETIUM-SULPHONAMIDE COMPLEXES, THEIR USE, PHARMACEUTICAL AGENTS CONTAINING THEM, AND PROCESS FOR PRODUCING THE COMPLEXES AND AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996002500-A1 | TECHNETIUM-SULPHONAMIDE COMPLEXES, THEIR USE, PHARMACEUTICAL AGENTS CONTAINING THEM, AND PROCESS FOR PRODUCING THE COMPLEXES AND AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |