SCHEMBL8764047

SCHEMBL8764047

N#CSCc1ccc(Cc2ccc(CSC#N)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.36
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
CYP3A4 P08684 3/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
IDO1 P14902 2/20 0.35
MAPK1 P28482 2/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAOB P27338 4/20 0.33
MAOA P21397 2/20 0.33
SAE1 Q9UBE0 1/20 0.33
UBA2 Q9UBT2 1/20 0.33
HTT P42858 1/20 0.33
CALM1 P0DP23 1/20 0.33
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4941438 0.92 ALDH1A1 (0.40) TSHRALDH1A1TDP1IDO1MAPK1
SCHEMBL14396518 0.81 CYP2A6 (0.52) ALDH1A1IDO1TP53HPGDHSD17B10
SCHEMBL7939411 0.81 IDO1 (0.45) ALDH1A1IDO1MAPK1HPGDHTT
SCHEMBL28637924 0.81 MAOB (0.52) ALDH1A1IDO1HPGDSMN1; SMN2HSD17B10
SCHEMBL4921123 0.81 MAOA (0.52) ALDH1A1IDO1MAPK1MAOBMAOA
SCHEMBL28710323 0.81 MAOA (0.52) ALDH1A1IDO1TP53SMN1; SMN2MAOB
SCHEMBL13001469 0.81 ESR1 (0.44) ALDH1A1TDP1CYP3A4ESR1ESR2
Benzyl Thiocyanate SCHEMBL27730692 0.80 MAOB (0.48) TSHRALDH1A1IDO1HPGDHSD17B10
Benzyl Thiocyanate SCHEMBL129196 0.80 MAOB (0.48) TSHRALDH1A1IDO1HPGDHSD17B10
Benzyl Thiocyanate SCHEMBL11858619 0.78 MAOB (0.47) TSHRALDH1A1IDO1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0349195-B1 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC (US) 1997-05-21 EP disclosed
US-5629394-A ENDCAPPING ADDITION POLYMERS WITH NITROGEN FUNCTIONAL GROUPS WHICH CAN BE FURTHER DERIVATIZED EXXON CHEMICAL PATENTS INC (US) 1997-05-13 US disclosed
US-5444135-A Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously EXXON CHEMICAL PATENTS INC. (US) 1995-08-22 US disclosed
US-5336745-A Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators EXXON CHEMICAL PATENTS INC. (US) 1994-08-09 US disclosed
US-5032653-A Catalysts EXXON CHEMICAL PATENTS, INC. (US) 1991-07-16 US disclosed
EP-0349195-A2 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC. (US) 1990-01-03 EP disclosed