Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762760 | 0.76 | ALDH1A1 (0.42) | GRM2GRM3 | |
| SCHEMBL8902260 | 0.73 | CYP19A1 (0.38) | CYP19A1NPC1RAB9A | |
| SCHEMBL8763747 | 0.72 | PTGS1 (0.39) | NPC1RAB9A | |
| SCHEMBL8763834 | 0.72 | — | — | |
| SCHEMBL8764427 | 0.70 | HSD11B1 (0.31) | — | |
| SCHEMBL7057956 | 0.69 | KDM4E (0.45) | GRM2GRM3 | |
| SCHEMBL7734241 | 0.68 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL7058342 | 0.65 | MAPT (0.47) | GRM2GRM3 | |
| SCHEMBL7058347 | 0.65 | MAPT (0.47) | GRM2GRM3 | |
| SCHEMBL7734160 | 0.64 | HSD17B3 (0.42) | SLC1A2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |