SCHEMBL8764396

SCHEMBL8764396

CC(=O)OCC(CNC(=O)c1c(I)c(N)c(I)c(N[C]=O)c1I)OC(C)=O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.32
LMNA P02545 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9515975 0.88 ABCB1 (0.37) ABCB1LMNACYP2C19HIF1A
SCHEMBL1359798 0.88 LMNA (0.38) ABCB1LMNACYP2C19HIF1A
SCHEMBL8377049 0.87 LMNA (0.36) ABCB1LMNACYP2C19HIF1A
SCHEMBL8378374 0.87 LMNA (0.34) ABCB1LMNACYP2C19HIF1A
SCHEMBL4927394 0.87 LMNA (0.38) ABCB1LMNACYP2C19HIF1A
SCHEMBL8374414 0.86 LMNA (0.34) ABCB1LMNACYP2C19HIF1A
SCHEMBL28880448 0.84 LMNA (0.36) ABCB1LMNACYP2C19HIF1A
SCHEMBL8063052 0.83 LMNA (0.36) ABCB1LMNACYP2C19HIF1A
SCHEMBL9009046 0.82 LMNA (0.35) ABCB1LMNACYP2C19HIF1A
Hydrochloric Acid SCHEMBL8857263 0.82 LMNA (0.35) ABCB1LMNACYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0782565-A1 IODINATED X-RAY-CONTRAST MEDIA NYCOMED IMAGING AS (NO) 1997-07-09 EP disclosed
WO-1996009285-A1 IODINATED X-RAY-CONTRAST MEDIA NYCOMED IMAGING AS (NO) 1996-03-28 WO disclosed