Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557823 | 0.81 | KDM4E (0.49) | KDM4EDGAT1SOAT1KCNH2EPHX2 | |
| SCHEMBL12342923 | 0.78 | KDM4E (0.51) | KDM4EDGAT1SOAT1KCNH2EPHX2 | |
| SCHEMBL8764554 | 0.76 | PSMB8 (0.42) | KDM4EMEN1ALDH1A1ALOX15KMT2A | |
| SCHEMBL8763571 | 0.76 | NQO2 (0.48) | KDM4EBACE1MEN1ALDH1A1ALOX15 | |
| SCHEMBL8626980 | 0.74 | ALDH1A1 (0.42) | KDM4EMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL6107899 | 0.72 | KDM4E (0.72) | KDM4EDGAT1KCNH2EPHX2SCN4A | |
| SCHEMBL8764555 | 0.72 | KDM4E (0.53) | KDM4EMEN1ALDH1A1ALOX15KMT2A | |
| SCHEMBL12340096 | 0.72 | KDM4E (0.42) | KDM4EDGAT1SOAT1KCNH2EPHX2 | |
| SCHEMBL12355859 | 0.72 | KDM4E (0.66) | KDM4EDGAT1KCNH2EPHX2SCN4A | |
| SCHEMBL12355858 | 0.72 | KDM4E (0.66) | KDM4EDGAT1KCNH2EPHX2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784083-A2 | Composition and use of substituted 1,3-dithiolo-and 1,4-dithiinoquinoxalines as an antimicrobial | THE DOW CHEMICAL COMPANY (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0573635-A1 | COMPOSITION AND USE OF SUBSTITUTED 1,3-DITHIOLO- AND 1,4-DITHIINOQUINOXALINES AS AN ANTIMICROBIAL | THE DOW CHEMICAL COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| WO-1993013106-A1 | COMPOSITION AND USE OF SUBSTITUTED 1,3-DITHIOLO- AND 1,4-DITHIINOQUINOXALINES AS AN ANTIMICROBIAL | THE DOW CHEMICAL COMPANY (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5200409-A | For preventing growth of marine organisms on an exposed surface | THE DOW CHEMICAL COMPANY (US) | 1993-04-06 | — | — | US | disclosed |