Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 3/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763571 | 0.79 | NQO2 (0.48) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL8763580 | 0.79 | PSMB8 (0.40) | PSMB8PSMB5PIK3CGKMT2AKDM4E | |
| SCHEMBL8626980 | 0.77 | ALDH1A1 (0.42) | PSMB8KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL4603580 | 0.76 | PSMB8 (0.49) | PSMB8PSMB5PIK3CGKMT2AKDM4E | |
| SCHEMBL8764487 | 0.76 | KDM4E (0.49) | KMT2AKDM4EMEN1ALDH1A1HSD17B10 | |
| SCHEMBL8764555 | 0.76 | KDM4E (0.53) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL5157381 | 0.72 | PIK3CG (0.58) | PIK3CGKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL8555964 | 0.69 | PGK1 (0.51) | KMT2AMAPTALDH1A1MAPK1LMNA | |
| SCHEMBL3993929 | 0.69 | PSMB8 (0.42) | PSMB8PSMB5PIK3CGKMT2AKDM4E | |
| SCHEMBL3994244 | 0.69 | PSMB8 (0.42) | PSMB8PSMB5PIK3CGKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784083-A2 | Composition and use of substituted 1,3-dithiolo-and 1,4-dithiinoquinoxalines as an antimicrobial | THE DOW CHEMICAL COMPANY (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0573635-A1 | COMPOSITION AND USE OF SUBSTITUTED 1,3-DITHIOLO- AND 1,4-DITHIINOQUINOXALINES AS AN ANTIMICROBIAL | THE DOW CHEMICAL COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| WO-1993013106-A1 | COMPOSITION AND USE OF SUBSTITUTED 1,3-DITHIOLO- AND 1,4-DITHIINOQUINOXALINES AS AN ANTIMICROBIAL | THE DOW CHEMICAL COMPANY (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5200409-A | For preventing growth of marine organisms on an exposed surface | THE DOW CHEMICAL COMPANY (US) | 1993-04-06 | — | — | US | disclosed |