SCHEMBL8764498

SCHEMBL8764498

CN(C)c1nc(Nc2cccc(N)c2)nc(Nc2cccc(N)c2)n1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH2 P48735 2/20 0.62
ALDH1A1 P00352 2/20 0.60
GAA P10253 3/20 0.50
TERT O14746 1/20 0.50
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
POLB P06746 2/20 0.49
XBP1 P17861 1/20 0.49
HTT P42858 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
SYK P43405 1/20 0.49
KDM4E B2RXH2 1/20 0.49
GFER P55789 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
ABL1 P00519 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30925067 1.00 IDH2 (0.62) IDH2ALDH1A1GAATERTKMT2A
SCHEMBL30562909 1.00 IDH2 (0.62) IDH2ALDH1A1GAATERTKMT2A
SCHEMBL23130552 0.92 ALDH1A1 (0.55) IDH2ALDH1A1GAATERTKMT2A
SCHEMBL11795454 0.86 MEN1 (0.63) IDH2GAAKMT2AMEN1LMNA
SCHEMBL31302305 0.86 MEN1 (0.63) IDH2GAAKMT2AMEN1LMNA
SCHEMBL21496112 0.85 SYK (0.51) IDH2ALDH1A1GAAKMT2AMEN1
SCHEMBL13917178 0.84 FCGR3B (0.71) IDH2ALDH1A1GAATERTPOLB
SCHEMBL11582771 0.84 KMT2A (0.52) IDH2ALDH1A1GAAKMT2AMEN1
SCHEMBL31149854 0.83 CFTR (0.53) IDH2GAATERTKMT2AMEN1
SCHEMBL16010929 0.83 CFTR (0.53) IDH2GAATERTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113912847-B Polymer, liquid crystal aligning agent, liquid crystal alignment film and application of liquid crystal alignment film 波米科技有限公司 2024-06-18 CN claimed
US-20250163218-A1 POLYIMIDE PRECURSOR FOR DISPLAY SUBSTRATE, POLYIMIDE FILM FOR DISPLAY SUBSTRATE, AND DISPLAY SUBSTRATE UBE CORPORATION (JP) 2025-05-22 US disclosed
CN-113912847-B Polymer, liquid crystal aligning agent, liquid crystal alignment film and application of liquid crystal alignment film 波米科技有限公司 2024-06-18 CN disclosed
CN-113912847-A Polymer, liquid crystal aligning agent, liquid crystal alignment film and application of liquid crystal alignment film 波米科技有限公司 2022-01-11 CN disclosed
US-10174166-B2 Polyimide precursor, polyimide, varnish, polyimide film, and substrate UBE INDUSTRIES, LTD. (JP) 2019-01-08 US disclosed
US-9511565-B2 Polyimide precursor, polyimide, polyimide film, and method for manufacturing triazine compound used for manufacturing same UBE INDUSTRIES, LTD. (JP) 2016-12-06 US disclosed
US-20150361222-A1 POLYIMIDE PRECURSOR, POLYIMIDE, VARNISH, POLYIMIDE FILM, AND SUBSTRATE UBE CORPORATION (JP) 2015-12-17 US disclosed
US-20140255710-A1 POLYIMIDE PRECURSOR, POLYIMIDE, POLYIMIDE FILM, AND METHOD FOR MANUFACTURING TRIAZINE COMPOUND USED FOR MANUFACTURING SAME NATIONAL UNIVERSITY CORPORATION IWATE UNIVERSITY (JP) 2014-09-11 US disclosed
EP-2535367-A1 POLYIMIDE FILM, POLYIMIDE LAMINATE COMPRISING SAME, AND POLYIMIDE/METAL LAMINATE COMPRISING SAME Ube Industries, Ltd. (JP) 2012-12-19 EP disclosed
US-20120308816-A1 POLYIMIDE FILM, POLYIMIDE LAMINATE COMPRISING SAME, AND POLYIMIDE/METAL LAMINATE COMPRISING SAME UBE INDUSTRIES, LTD. (JP) 2012-12-06 US disclosed
EP-0632104-A1 Basic azodyes BAYER AG (DE) 1995-01-04 EP disclosed
EP-0103739-B1 CATIONIC DYESTUFFS, THEIR PREPARATION AND THEIR USE BAYER AG (DE) 1989-07-19 EP disclosed
US-4110294-A POLYIMIDES CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-4105646-A α,β-Unsaturated schiff-base chain extension reactions for high temperature polymers CIBA-GEIGY CORPORATION (US) 1978-08-08 US disclosed
US-4066609-A GLASS FABRIC OR FIBER CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed
US-3993630-A Polyimide, polyamide-imide or polyamide-acids with olefin end groups in combination with a reactive Schiff base compound CIBA-GEIGY CORPORATION (US) 1976-11-23 US disclosed
US-3979350-A MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1976-09-07 US disclosed
US-3957726-A S-TRIAZINE-IMIDE COPOLYMERS CIBA-GEIGY CORPORATION (US) 1976-05-18 US disclosed
US-3944525-A Crosslinked resins prepared from an N,N'-bis-imide and a schiff base CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed
US-3943107-A Processable high temperature polymers prepared from amine terminated polymers and cyanamides of polyfunctional secondary amines CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140255710-A1 POLYIMIDE PRECURSOR, POLYIMIDE, POLYIMIDE FILM, AND METHOD FOR MANUFACTURING TRIAZINE COMPOUND USED FOR MANUFACTURING SAME F12, TERB1, PBRM1 IDH2 2329/4885ALDH1A1 684/4885GAA 3468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.