SCHEMBL8764595

SCHEMBL8764595

CC(C)OOP(=O)(COS(=O)(=O)c1c(Cl)cccc1Cl)OOC(C)C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.32
NR1H4 Q96RI1 2/20 0.31
CXCR2 P25025 1/20 0.30
NR3C1 P04150 1/20 0.30
PGR P06401 1/20 0.30
NR3C2 P08235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764522 0.95 KMT2A (0.32) KMT2A
SCHEMBL8764545 0.93
SCHEMBL8763949 0.92 NR3C1 (0.34) KMT2ANR3C1
SCHEMBL8764040 0.91 NR1H4 (0.30) NR1H4
SCHEMBL8762722 0.88 NR3C1 (0.32) KMT2ANR3C1
SCHEMBL8764048 0.88 KMT2A (0.32) KMT2ANR1H4CXCR2
SCHEMBL8764717 0.87 KMT2A (0.30) KMT2A
SCHEMBL8764078 0.86 RORC (0.32) NR3C1
SCHEMBL8734923 0.86 SMN1; SMN2 (0.38) KMT2ANR1H4CXCR2NR3C1PGR
SCHEMBL8762813 0.85 KMT2A (0.31) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP claimed