Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313913 | 0.88 | CYP1A2 (0.51) | TRPV4CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL6682849 | 0.83 | TRPV4 (0.60) | TRPV4CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL31494541 | 0.83 | TRPV4 (0.60) | TRPV4CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL5406327 | 0.80 | TRPV4 (0.61) | TRPV4CYP1A2CYP2C19L3MBTL1MAPT | |
| SCHEMBL10183556 | 0.78 | CYP2C19 (0.49) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL25045969 | 0.78 | TRPV4 (0.63) | TRPV4L3MBTL1MAPTLMNAATM | |
| SCHEMBL16469895 | 0.76 | TRPV4 (0.61) | TRPV4MAPTHPGDLMNAALDH1A1 | |
| SCHEMBL29587888 | 0.76 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL24314195 | 0.76 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL25362679 | 0.75 | MCL1 (0.51) | TRPV4CYP1A2CYP2C19L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511826-B1 | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-07-16 | — | — | EP | disclosed |
| US-5500405-A | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1996-03-19 | — | — | US | disclosed |
| US-5272128-A | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0511826-A2 | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1992-11-04 | — | — | EP | disclosed |