Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24314192 | 0.87 | TRPV4 (0.50) | TRPV4MAPTALDH1A1NPSR1LMNA | |
| SCHEMBL29588407 | 0.83 | CA12 (0.50) | TRPV4MAPTALDH1A1NPSR1LMNA | |
| SCHEMBL22587747 | 0.83 | CA12 (0.50) | TRPV4MAPTALDH1A1NPSR1LMNA | |
| SCHEMBL25045969 | 0.81 | TRPV4 (0.63) | TRPV4MAPTALDH1A1NPSR1LMNA | |
| SCHEMBL30002818 | 0.81 | TRPV4 (0.66) | TRPV4ALDH1A1LMNAHTTPOLB | |
| SCHEMBL1817556 | 0.81 | TRPV4 (0.66) | TRPV4ALDH1A1LMNAHTTPOLB | |
| SCHEMBL16469895 | 0.80 | TRPV4 (0.61) | TRPV4MAPTALDH1A1LMNAHTT | |
| SCHEMBL8764653 | 0.80 | TRPV4 (0.57) | TRPV4MAPTALDH1A1NPSR1LMNA | |
| SCHEMBL31511099 | 0.79 | TRPV4 (0.55) | TRPV4MAPTALDH1A1NPSR1HTT | |
| SCHEMBL8726763 | 0.79 | TRPV4 (0.55) | TRPV4MAPTALDH1A1NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-RE39607-E1 | Herbicidal sulphonylamino(thio) carbonyl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2007-05-01 | — | — | US | disclosed |
| US-RE39607-E1 | Herbicidal sulphonylamino(thio) carbonyl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2007-05-01 | — | — | US | disclosed |
| US-RE39607-E1 | Herbicidal sulphonylamino(thio) carbonyl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2007-05-01 | — | — | US | disclosed |
| US-6525211-B1 | Chemical intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-25 | — | — | US | disclosed |
| US-6251831-B1 | WITH SUBSTITUTED PHENYL AND SUBSTITUTED 1,2,4-TRIAZOLE MOIETIES; PRE- AND POST-EMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |