Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10451316 | 0.82 | AR (0.49) | MAOBARCA12CA1CA2 | |
| SCHEMBL29749364 | 0.82 | AR (0.49) | MAOBARCA12CA1CA2 | |
| SCHEMBL8764099 | 0.79 | KCNK3 (0.46) | ARMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL30093322 | 0.79 | CA1 (0.55) | MAOBARCA12CA1CA2 | |
| SCHEMBL255270 | 0.79 | CA1 (0.55) | MAOBARCA12CA1CA2 | |
| SCHEMBL11612177 | 0.78 | ALDH1A1 (0.39) | CA2SMN1; SMN2TSHRLMNAMAPT | |
| SCHEMBL1142161 | 0.78 | CA1 (0.58) | CA12CA1CA2CA4CA7 | |
| SCHEMBL4511619 | 0.78 | AR (0.44) | MAOBARCA12CA1CA2 | |
| SCHEMBL9952870 | 0.78 | AR (0.44) | MAOBARCA12CA1CA2 | |
| SCHEMBL16049413 | 0.78 | AR (0.44) | MAOBARCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908846-B2 | Composition, synthesis, and use of new arylsulfonyl isonitriles | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2018-03-06 | — | — | US | disclosed |
| US-20150239833-A1 | COMPOSITION, SYNTHESIS, AND USE OF NEW ARYLSULFONYL ISONITRILES | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 2015-08-27 | — | — | US | disclosed |
| EP-0511826-B1 | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-07-16 | — | — | EP | disclosed |
| US-5500405-A | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1996-03-19 | — | — | US | disclosed |
| US-5272128-A | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0511826-A2 | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1992-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239833-A1 | COMPOSITION, SYNTHESIS, AND USE OF NEW ARYLSULFONYL ISONITRILES | SRMS, AADAC, CYP3A4 | MAOB 2438/4885AR 957/4885CA12 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.