Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.63 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764755 | 0.93 | GRM2 (0.60) | GRM2GRM3FFAR4FAAHCCR8 | |
| SCHEMBL8764501 | 0.83 | GRM2 (0.75) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8763689 | 0.82 | GRM2 (0.59) | GRM2GRM3FFAR4GRM8GRM4 | |
| SCHEMBL8762578 | 0.80 | GRM2 (0.56) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8764744 | 0.79 | GRM2 (0.65) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8892624 | 0.79 | GRM2 (0.65) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8762579 | 0.79 | GRM2 (0.63) | GRM2GRM3FAAHGRM8GRM4 | |
| SCHEMBL8763907 | 0.79 | GRM2 (0.69) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8764032 | 0.77 | GRM2 (1.00) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8891901 | 0.77 | GRM2 (1.00) | GRM2GRM3GRM8GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |