SCHEMBL8764675

SCHEMBL8764675

CCP(=O)(COS(=O)(=O)c1c(OC)cccc1C(F)(F)F)OOC(C)C

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.32
ATM Q13315 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
HPGD P15428 1/20 0.31
NFE2L2 Q16236 2/20 0.31
LMNA P02545 1/20 0.30
KCNK3 O14649 1/20 0.30
KCNK9 Q9NPC2 1/20 0.30
PDE4B Q07343 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8729954 0.90 CTSS (0.34) CTSSATMSMN1; SMN2HPGDNFE2L2
SCHEMBL8764702 0.88 SMN1; SMN2 (0.32) ATMSMN1; SMN2HPGDNFE2L2LMNA
SCHEMBL8764036 0.87 SMN1; SMN2 (0.32) ATMSMN1; SMN2HPGDNFE2L2
SCHEMBL8764008 0.87 CTSS (0.31) CTSS
SCHEMBL8763952 0.85 SMN1; SMN2 (0.31) SMN1; SMN2HPGDNFE2L2
SCHEMBL8763768 0.85 KCNK3 (0.31) ATMKCNK3KCNK9
SCHEMBL8763812 0.81 MEN1 (0.35)
SCHEMBL8731887 0.81 NFE2L2 (0.35) CTSSATMSMN1; SMN2HPGDNFE2L2
SCHEMBL8734756 0.81 KCNK3 (0.40) KCNK3KCNK9
SCHEMBL8729845 0.81 SMN1; SMN2 (0.33) CTSSATMSMN1; SMN2HPGDNFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP claimed